MEBIAS, an emerging leader in the field of pathway-selective G-protein coupled receptor (GPCR) drug discovery, was founded in January 2016 by 3 highly experienced drug discovery scientists, formerly of Johnson & Johnson and Merck. The ability to accurately design GPCR-targeting medicines with well-established mechanisms that avoid specific side effects within a therapeutic index — known as pathway-selective drug discovery — presents a unique opportunity with lower risk than utilizing traditional techniques to explore new, non-validated mechanisms. Initial areas of focus for MEBIAS are Neuroscience/Pain, Metabolic, Gastroparesis, and Inflammatory-related disorders.